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A New Indication for Semaglutide (Wegovy) The injectable glucagon-like peptide-1 (GLP-1) receptor agonist semaglutide (Wegovy) has been approved by the FDA to reduce the risk of major adverse cardiovascular events (MACE) in adults with established cardiovascular disease (CVD) and either obesity or overweight

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Both are observational, the ACR one is a conference abstract, and at least one database study has flagged a possible short-term rise in new-onset RA early in therapy

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