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11/03/2025 Electronic publication Footnotes Conflict of interest: DJD has received consulting fees from Anylam, Amgen, AstraZeneca Inc., Crinetics, Eli Lilly, Insulet, Kallyope, Metsara, and Pfizer Inc

Thyroid cancer Although only observed in animal studies, GLP-1-RAs can lead to thyroid C-cell hyperplasia and malignancies

However, genetics influence your susceptibility: the PlexusDx Precision Peptide Genetic Test identifies variants in GLP1R and MC4R that predict your individual risk, allowing your doctor to plan your dose escalation more strategically from day one

In addition to causing severe coughing and other symptoms, the thickened lung tissue prevents oxygen from diffusing into the bloodstream

GLP-1 medications act like the natural hormone in your body and interact with receptors found mostly in your gut, brain, and pancreas