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Treatment begins at a low dose (2.5 mg weekly) and is gradually increased every four weeks (to 5 mg, 7.5 mg, 10 mg, 12.5 mg, and 15 mg) as tolerated to minimize gastrointestinal side effects

For now, though, the responsible position is to lean on what is proven while keeping an eye on what is promising

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A: While there are no specific dietary restrictions, maintaining a balanced diet and regular exercise is recommended to optimize the effects of the medication

Both GLP-1R (70, 71) and GIPR (72, 73) are expressed in the LS, and peripherally administered GLP-1R agonists can reach this region (21, 74, 75)