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Due to the promotive effect of GLP-1R agonism on -cells proliferation and survival, concerns of tumorigenesis, especially pancreatic cancers, have been raised about incretin-based therapies (93)

61 Compared with magnetic resonance imaging-proton density fat fraction (MRI-PDFF), the CAP thresholds of 288 dB/m and 306 dB/m correlate with 5% and 10% steatosis respectively

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Specifically, GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide) receptor agonists are instrumental in managing hunger, stabilizing blood sugar, and enhancing fat metabolism