glp 1 and gip hormones GLP-1 as incretin hormones: lessons from single and double incretin receptor knockout mice Targeting both incretin receptors together

Genetic engineering creates new opportunities In the early 1970s a new tool appeared on the scene called recombinant DNA technology or genetic engineering

17 These medications are often highly regarded by patients for their striking benefits, not only in terms of weight reduction but also of improving associated comorbidities such as hypertension, diabetes, depression, and anxiety

There is a risk of contamination and overdosing due to the lack of standardization

Meanwhile, research on the mechanism and efficacy of GLP-1R/GIPR dual agonists and GLP-1R/GIPR/GCGR triple agonists paves the way to a ground-breaking therapy specific for obesity, which suggests multi-target drugs may have more advantages than a single target

4 Cardiovascular Risk Reduction In addition to managing blood glucose levels and promoting weight loss, GLP-1 receptor agonists have been found to reduce the risk of cardiovascular events, which is a critical consideration in diabetic patients