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GLP-1 medications work through incretin hormone mimicry

Mice were tested to quantify nociceptive threshold on days 7 and 10 in the short-term model and on days 14, 21, and 28 after injection of MIA or saline in the long-term model
however, their role may be more pharmacological than physiological

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Under cholesterol stimulation, GLP-1-induced AMPK activation inhibited PARP-1 activity, therefore attenuating cholesterol-induced toxicity in INS-1 cells
