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Metabolism 62, 922934

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Rai said the additional five years, stretching the patent from 2026 to 2031, likely stem from the Hatch-Waxman Act, a 1984 law that allows drugmakers to extend patents by up to five years to make up for time lost moving their drug through clinical trials and the FDA approval process

The firm says that the pill is more convenient than the widespread use of GLP-1 injections, and that it does not need to be stored in a fridge

Mechanistically, syndecans induce protein kinase C-alpha (PKC)-dependent phosphorylation of a conserved serine residue in the cytoplasmic domain of TRPC channels 3