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Kherkher Garcia

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Quantification of the contribution of GLP-1 to mediating insulinotropic effects of DPP-4 inhibition with vildagliptin in healthy subjects and patients with type 2 diabetes using exendin [939] as a GLP-1 receptor antagonist

Our analysis had shown moderate heterogeneity among studies for this outcome

Specifically, we found GLP-1R agonist pharmacotherapy increased VTA GABA neuron activity associated with cocaine seeking and suppressed cocaine-seeking evoked increases in VTA dopamine neuron activity