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For some participants, samples were not shipped to SomaLogic for analysis due to lack of consent or availability of samples in the storage facility upon the cutoff date for the use of samples

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Sildanefil can be given IV if a patient is NPO

A 3-4 day weekly program focused on compound lifts (squats, deadlifts, presses, rows) with progressive overload in the 6-12 rep range at 10-16 hard sets per muscle group weekly is optimal for muscle preservation during GLP-1 therapy

This step cannot be bypassed and is fundamental to safe treatment