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Rest/Stress myocardial perfusion imaging with PET has certain advantages over SPECT: Improved spatial resolution Ability to acquire stress images at peak stress if using dobutamine (versus lag time with SPECT) Absolute myocardial blood flow quantification with PET (not available with SPECT where perfusion is relative) With PET we can use either Rubidium-82 (half-life = 76 sec) or N-13 Ammonia (half-life = 10 min) as tracers to assess myocardial perfusion

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