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Phase 2 data suggests retatrutide may produce greater weight reduction than currently approved agents, but its long-term safety profile has not been fully established, and no head-to-head regulatory-grade trials have been completed

[DOI] [PMC free article] [PubMed] [Google Scholar] 2.Zheng H., Berthoud H.R

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Hypoglycemia risk increases in patients with type 2 diabetes, particularly those taking insulin or sulfonylureas alongside GLP-1 therapy