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Ozempic is a medication in a class called GLP-1 (glucagon like peptide) receptor agonists

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Although Glp1r expression is mostly localized to endothelial cells in the mouse aorta (29), other vascular cell types may express Glp1r under atherogenic conditions, making it difficult to pinpoint which cell type mediates the antiinflammatory effects of GLP-1 medicines

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We hope that this work will help us understand why these receptors work differently to each other, why they have different strengths at triggering the release of insulin and glucagon, and how changes in the genes that code for them modify the way they work in specific people.