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However, like any medication, GLP-1s come with possible side effects, including: Nausea Vomiting Constipation Pancreatitis Diarrhea Injection site reaction Hair loss Headache Muscle loss Fatigue Anhedonia (lack of joy in eating and other life activities) For a comprehensive list of efficacy and safety data, review the prescribing information for each medication or visit the FDA Adverse Event Reporting System website

Losing muscle reduces your metabolic rate, making continued weight loss harder and increasing the likelihood of regain later

GLP-1 is produced through the proteolytic processing of proglucagon, promoting insulin secretion while inhibiting glucagon production

A healthcare provider should monitor labs and symptoms closely