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At the same time, transformation stories online often underplay the less glamorous realities: Muscle loss alongside fat loss Nutritional compromise from severely reduced intake Hair loss, fatigue, nausea, and GI adverse effects Weight regain after discontinuation Psychological pressure surrounding body image Unsupervised or socially influenced use Perhaps the most important point: these medications were never meant to replace lifestyle modification

Conclusion Oral semaglutide was effective at lowering HbA1c and body weight, regardless of background medications, and appears suitable for a broad range of patients with T2D in combination with other glucose-lowering agents

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Wegovy (semaglutide) should be used with caution in patients with muscular dystrophy due to potential concerns about muscle mass loss, though there is insuff...