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Description
The introduction of tirzepatide, the first dual agonist targeting both the GLP-1R and the glucose-dependent insulinotropic polypeptide (GIP) receptor, represents a new frontier in incretin-based therapy (Syed, 2022

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If you have taken your injection early and experience any unusual or severe symptoms, contact your GP or NHS 111 for advice

More GLP-1 was needed to achieve the same biological effect, indicating the participants were GLP-1-resistant

[DOI] [PMC free article] [PubMed] [Google Scholar] 230.Elkind-Hirsch K., et al
