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SELECT, Semaglutide Effects on Cardiovascular Outcomes in People With Overweight or Obesity (SELECT) trial

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Compounded semaglutide has a 28-day shelf life after first use (some pharmacies extend to 60 days with specific preservative systems), so stockpiling more than 8 weeks of supply is impractical

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(2018) J Med Chem 61 : 5580-5593 PubMed: 29879354 Search on PubMed DOI: Primary Citation Related Structures: 6GB1, 6GDZ, 6GE2 PubMed Abstract: Novel peptidic dual agonists of the glucagon-like peptide 1 (GLP-1) and glucagon receptor are reported to have enhanced efficacy over pure GLP-1 receptor agonists with regard to treatment of obesity and diabetes

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