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GLP-1 therapy addresses not only weight reduction but also helps regulate blood sugar patterns, which becomes increasingly relevant as insulin sensitivity naturally declines after age 30

While the kinetic rate constants could not be accurately determined for GLP-1 QMP, GLP-1 QMP/LX (0.2 nM) showed an almost 600-fold higher binding affinity compared to GLP-1 WT (Fig

Acta Diabetol 2015;52:649e62

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The drawbacks of the GLP-1 RAs include the subcutaneous administration, the gastrointestinal side effects, and the cost