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Bariatric surgery is the most effective treatment in severely obese patients, inducing significant improvement in lobular inflammation and a disappearance of NASH in 5085% of cases (41)

The placebo group recorded only a 4.5% reduction in total fat mass, while retatrutide recipients saw fat mass fall by 15.2% in the 4mg group, 26.1% in the 8mg group and 23.2% in the 12mg group

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