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Beyond neurodegeneration, GLP-1RAs are being investigated for broader neurological conditions, including stroke and traumatic brain injury, due to their neuroprotective and anti-inflammatory properties [69,70]

Semaglutide follows a gradual 4-week titration: Start 0.25mg weekly (weeks 1-4), increase to 0.5mg (weeks 5-8), then 1mg (weeks 9-12), 1.7mg (weeks 13-16), and maintain 2.4mg weekly
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