sglt2 inhibitors and glp-1 receptor agonists Effect of combination treatment with glucagon-like peptide-1 sodium-glucose cotransporter-2 on incidence of cardiovascular and serious renal events: population based cohort study Mechanisms underlying favorable effects of
Description
A meta-analysis of GLP-1RA CVOT showed that treatment with GLP-1RA reduced the risk of developing a composite kidney outcome including new-onset MA by 21% compared to placebo (HR 0.79, 95% CI 0.73-0.87), with only ELIXA and EXSCEL not achieving significant benefit [11]
The choice often comes down to personal preference and lifestyle
Focus on delaying/ preventing T1D Zealand Pharma US Inc
One of the first dedicated investigations aimed at uncovering modification sites in the topology of a representative DPP-8/9 inhibitor capable of imparting selectivity for DPP-8 over DPP-9 was conducted by Van Goethem et al
doi: 10.3389/fendo.2022.1043789 108 WhartonSDaviesMDickerDLingvayIMosenzonORubinoDMet al
