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At the same time, oral GLP-1 therapies such as Eli Lillys orforglipron may significantly broaden treatment access

doi:10.1002/jnr.10611 269

Recently, GLP-1RAs have been approved for the treatment of obesity and recognized for their cardioprotective effects

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Throughout the duration of the simulations, ECL1 and ECL3 maintained most of their original helical structure except for certain motions along with the adjacent transmembrane helices and the opposing ECD