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Neelapu BC, Kharbanda OP, Sardana HK, et al
The appropriate response is not avoidance, but disciplined translational design that aligns mechanism, indication, and risk tolerance
a detailed description of this study is reported elsewhere 52
Nearly all PCOS patients prescribed semaglutide or tirzepatide also had obesity or type 2 diabetes, suggesting use remains primarily tied to metabolic indications, though broader interest in PCOS benefits is growing within scientific literature
These lipid modifications, along with the weight loss induced by retatrutide, contribute to a more favorable cardiovascular profile
