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Tirzepatide is engineered as a single molecule that activates both receptors rather than being two separate medications combined

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Serious hypoglycemia (blood glucose less than 54 mg/dL) in SURPASS-4 was reported less (9%) in individuals on tirzepatide than in individuals on insulin glargine (19%)

Using databases such as PubMed, Scopus, CINAHL, PEDro, Cochrane Library, SCIELO, and EMBASE, we screened studies focused on both sleep-related and diabetic foot outcomes