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This chemosensor, together with other 27 non-selective cationic channels, is part of a larger family named transient receptor potential (TRP) channel superfamily and is known to play an important role in the metabolic syndrome (361, 362)
In addition, the heterogeneity in study designs, patient populations, condition, and outcome measures from the studies herein analyzed further complicates direct comparisons and limits the possibility of drawing solid conclusions
On the other hand, the use of GLP-1 RAs has been shown to be correlated with emotional eating and depression in patients with diabetes and obesity (35)
