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We also see with PMDD, which is a extreme, extreme form of PMS, and even saying that is not doing its service in how bad it is, there's GABA alpha receptor dysfunction, and so allopregnanolone doesn't dock appropriately in the brain with endometriosis

The expanding burden of idiopathic intracranial hypertension

The current evidence doesnt suggest you should avoid Wegovy if youre taking sertraline, but it does highlight the importance of: Continuing your prescribed antidepressant treatment Monitoring your mood, particularly in the first few months Keeping your GP informed about any changes in how youre feeling Not stopping sertraline without medical advice, even if you feel your mood has improved Practical tips for taking both medications If youre taking sertraline and starting Wegovy, here are some practical suggestions