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Those with type 1 diabetes or insulin-dependent type 2 diabetes must consult their endocrinologist before fasting on GLP-1s, as fasting reduces calorie intake and can increase hypoglycemia risk without medication adjustment

They include: pancreatic cancer, liver cancer, colorectal cancer, lung cancer and kidney cancer

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IL-6 deficiency attenuates skeletal muscle atrophy by inhibiting mitochondrial ROS production through the upregulation of PGC-1 in septic mice

For compounded medications, tirzepatide costs about $150/month more ($349 vs $199 at TrimRx)
