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N Engl J Med 375:18341844 Holman RR, Bethel MA, Mentz RJ, Thompson VP, Lokhnygina Y, Buse JB, Chan JC, Choi J, Gustavson SM, Iqbal N, Maggioni AP, Marso SP, hman P, Pagidipati NJ, Poulter N, Ramachandran A, Zinman B, Hernandez AF (2017) EXSCEL Study Group

Data representative of two independent experiments with Tm values calculated as the arithmetic mean and the standard deviation of the mean

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Higher risk factors were a history of type 2 diabetes, tobacco use and advanced chronic kidney disease ( stage 3)
