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Patients were randomized into three groups: one group received phentermine continuously for 36 weeks, another group received placebo continuously and the third group alternated phentermine and placebo every 4 weeks ( Figure 9 - 1 )

Neuroleptic malignant syndrome, a known complication of neuroleptic drugs or of abrupt discontinuation of dopaminergic agents, can cause rhabdomyolysis

Tirzepatide is a once-weekly injection with a half-life of approximately 5 days, so the drug is always present in your system between doses

Many of these foods are also rich in fiber, which can help with bowel regularityan important benefit when taking a GLP-1, says Charlie Seltzer, MD , a board-certified obesity medicine doctor in Philadelphia

Tirzepatide significantly reduces appetite and food intake, leading to substantial caloric deficits