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Cryo-EM data processing For the LSN3318839GLP-1(9-36)GLP-1RG s complex, the micrographs were processed using cryoSPARC v.4.4.121 with patch motion correction to restore the correct information of the original cryo-EM images

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Of note, most of these studies were conducted exclusively in younger adult male rodents

Some researchers use microdosing approaches to create even more gradual escalation