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Feb 11, 2026 Your vial arrived from Southend Pharmacy

Medium-chain 3-hydroxyacyl-CoA dehydrogenase deficiency (MHADD) Medium-chain fatty acid 3-hydroxyacyl-CoA dehydrogenase (MHADD) deficiency is a fairly rare disorder

The first time we saw this was during the liraglutide trials where blood pressure reduction occurred within 2 weeks of initiation of therapy, which was before any meaningful weight benefit was demonstrated suggesting that weight loss is not the driver of the blood pressure benefits

206,512 Thus, GLP-1 and its agonists slow down the progression of NASH and may positively impact the reversal of liver fibrosis

A study in a bariatric surgery cohort found that across multiple thresholds for weight regain assessed in the study, 20% or greater weight regain correlated best with worsening cardiometabolic risk factors [40]
