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Rosenkilde, MM (July 2021) 'The role of incretins on insulin function and glucose homeostasis', Endocrinology , 162/7, bqab065

Previous studies have demonstrated that the cAMP/p-AMPK/p-ACC and insulin-sensitizing pathways are pivotal to GLP-1s beneficial effects on hepatic lipid metabolism
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oxidative stress, calcium, and glutamate toxicity overload may also lead to energy deficiencies, forming a vicious cycle with -synuclein accumulation
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Valproic acid selectively inhibits conversion of arachidonic acid to arachidonoyl-CoA by brain microsomal long-chain fatty acyl-CoA synthetases: relevance to bipolar disorder

A patient who primarily needs short-term appetite suppression to kickstart a lifestyle change may do better on phentermine
