best glp-1 for menopause weight loss GLP-1s and the Menopause: What you need to know glp-1 weight loss treatment πβοΈ
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The 12mg group lost less fat mass than the 8mg group
10.1016/j.bbrc.2016.02.019 90
That is the practical payoff of a real small molecule
Although amino acid substitution is an effective strategy to reduce proteolytic degradation, modified GLP-1 analogs are still subject to rapid renal clearance, making it difficult to further prolong peptide circulation time
While Im excited about the future of these drugs development, the side effect profile isnt worth the risk for otherwise healthy patients
