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Erak, M., Bellmann-Sickert, K., Els-Heindl, S

The dose is typically higher in months 2 and 3 (moving toward 0.5 mg and then 1.0 mg weekly), which is when most patients report the strongest appetite suppression
These benefits are thought to result from improved blood glucose control, weight reduction, blood pressure lowering, and anti-inflammatory effects
Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin-secreting beta-cells
In the SUSTAIN trials, sensitivity analyses were conducted to assess the validity of MAR assumption and to evaluate the robustness of the conclusion of the primary analysis