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What the clinical trials tell us about injection sites The landmark phase 2 trial for retatrutide, published in the New England Journal of Medicine (Jastreboff et al., 2023), enrolled 338 adults with obesity
Semaglutide has also demonstrated impressive results, with 59% NASH resolution in a phase 2 trial and substantial reductions in hepatic fat content measured by MRI
Clinical guideline for the evaluation, management and long-term care of obstructive sleep apnea in adults
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The research suggests we should view these medications not just as weight loss drugs but as weight normalizing drugs that work through complex anti-inflammatory mechanisms
