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These medications have been known to mimic natural hormones in the body to help: Reduce hunger and food cravings Increase satiety (helping you feel fuller for longer) Improve insulin sensitivity and stabilize blood sugar levels Support fat loss, particularly in the abdominal area Potential Benefits of GLP-1 and GLP-1/GIP Injections Appetite Control & Craving Reduction These treatments may help control food noise , making it easier to manage portion sizes and reduce overeating

Placebo-controlled, randomized trial of the addition of once-weekly glucagon-like peptide-1 receptor agonist dulaglutide to titrated daily insulin glargine in patients with type 2 diabetes (AWARD-9) Diabetes Obes Metab

Most hepatic improvements correlate with the degree of weight loss, with limited evidence for weight-independent antifibrotic effects

They can also be used safely at low eGFR, and initiation or continuation in dialysis patients is associated with lower cardiovascular risk and mortality

For many patients, GLP-1 therapy is most effective when viewed as one part of a broader, long-term approach to metabolic health rather than a standalone solution with a defined end point.