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02Fiber and Bowel Changes Constipation, diarrhea, and the swing between them are common on a GLP-1

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Long-term application of GLP-1RAs may also elevate the release of endogenous GLP-2, which is a cell-specific growth hormone regulating the growth of the small intestine, colonic villi and crypts, increasing the length and weight of the small intestine, and reducing antral motility

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