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Reduced levels of the mitochondrial autophagy-associated protein Parkin in the substantia nigra may contribute to the development of Parkinsons disease (PD) in db/db mice and high-fat diet-induced diabetic mice.41 As discussed above, mitochondrial dysfunction (mitochondrial bioenergetics, calcium buffering) and mitochondrial quality control systems (mitochondrial dynamics, mitophagy, mitochondrial biogenesis) may be involved in the pathological mechanisms of diabetes-related NDs

With 63 active products in the pipeline, the race for the first approval is intensifying

Large, heavy meals Overeating can overwhelm the stomach, leading to discomfort

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