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Mechanism of action of GLP-1 receptor agonists: Direct receptor binding These medications bind specifically to GLP-1 receptors on pancreatic beta cells, stimulating insulin secretion in a glucose-dependent manner (meaning they work when blood glucose is elevated)

In the STEP UP clinical trial, the 7.2 mg dose produced a mean weight loss of 20.7% at 72 weeks, compared with 17.5% at the previously approved 2.4 mg dose and 2.4% with placebo

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Fill half your plate with fruits and vegetables to boost fiber intake