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Description
GLP-1-based therapies helped adults with overweight or obesity lose weight mainly by reducing fat mass and visceral adipose tissue, while lean body mass losses were generally modest

Five scientists won this years Breakthrough Prize in Life Sciences for their work on GLP-1 and the development of drugs for diabetes and obesity.

Ozempic is a popular GLP-1 drug for type 2 diabetes and is also commonly prescribed off-label for weight loss management
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This review - open access on Biological Psychiatry - synthesizes emerging clinical evidence and preclinical findings, highlighting the potential of GLP-1-based therapies to enhance quit rates and reduce cardiometabolic risk in individuals who smoke, particularly those with comorbid psychiatric or metabolic conditions
