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Risk of bias: all four RCTs were rated low risk by RoB2 (with some concerns for open-label outcome ascertainment in three trials, a domain-specific issue that does not alter the overall RoB2 category from low)

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Phase 2 trials in obesity and type 2 diabetes have been completed and published in major peer-reviewed medical journals, including data on body weight, glycemic markers, and tolerability

Drew Barrymore took to Instagram to gush over the fitness trainer who got her there: Marnie Alton, whom she calls one of the greats.