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Peripheral hypoxia in restless legs syndrome (WillisEkbom disease)
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NICE guidance (NG28) on type 2 diabetes management supports stepwise treatment escalation, with GLP-1-based therapies like Mounjaro typically reserved for patients who have not achieved adequate control with other agents
SGLT2i exert a complex cardioprotective mechanism independent from their antihyperglycemic effects

This is vital for individuals with type 2 diabetes, as tirzepatide mimics natural hormones to ensure insulin is released when needed
