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For researchers considering a broader incretin comparison, metabolic and energy research compounds at Sempica include retatrutide and MOTS-c alongside the GLP-1/GIP agonist class

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Ex-4 had 53% structural similarity with GLP-1 but could activate GLP-1 receptors (GLP-1R), and its longevity in the plasma was longer than that of GLP-1 [15]

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