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Reduction in androgen levels : Elevated androgen levels, such as testosterone, contribute to symptoms like hirsutism and acne in individuals with PCOS

This dual regulation of neurotrophic and insulin pathways may explain the significant neuroprotective effects seen with the combination, offering a mechanistic rationale for synergistic action rather than a merely additive benefit

Understanding the underlying causes can help you determine the best course of action and when to seek medical advice

The following is general guidance based on typical clinical use of oral semaglutide: Start with 3 mg once daily generally taken as an initial dose to help the body adjust

The drug is currently progressing through Phase 3 clinical development globally