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This is important because average trial results may not match the real-life experience of a 75-year-old who takes several medications and needs to manage appetite and hydration

These effects may contribute to cardiovascular outcomes

Persistence of Diabetes and Hypertension After Multimodal Treatment of Acromegaly
It is worth noting that for currently licensed GLP-1 receptor agonists in the UK, the thyroid tumour signal is classified as a precautionary consideration based on rodent data, rather than a formal contraindication as reflected in UK Summaries of Product Characteristics (SmPCs)

The gut microbiota and host health: a new clinical frontier
