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The FDA boxed warning specifically contraindicates certain GLP-1 receptor agonists in patients with a personal or family history of medullary thyroid carcinoma (MTC) or in patients with multiple endocrine neoplasia syndrome type 2 (MEN 2)

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Others remain cautious due to limited long-term utilization data and the likelihood that discontinuing medication may lead to weight regain

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Dipeptidyl peptidase-4 inhibitors and cardiovascular outcomes: meta-analysis of randomized clinical trials with 55,141 participants

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Long-acting GLP-1s (including Victoza, Trulicity, Bydureon, Ozempic, and Rybelsus) work to lower both post-meal and fasting blood sugar levels

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