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GLP-1 cuts appetite and slows digestion

The typical titration pathway involves four dose increases spaced four weeks apart, though your healthcare provider may adjust the timeline based on your individual tolerance and response

Obesity subtypes, related biomarkers & heterogeneity

Patients with diabetes or at risk of diabetes who require both medications should undergo regular blood glucose monitoring

SGLT2 inhibitors increase urinary glucose and water excretion and can precipitate euglycemic diabetic ketoacidosis, which may present with thirst, nausea, and vomiting even when blood glucose levels are not severely elevated