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Recent clinical trials further suggest that these agents may also have favourable effects on clinical outcomes in obese HFpEF patients

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Considerations and future directions The central histaminergic system has received considerable interest for its ability to regulate energy balance, however, many unanswered questions remain

Cardiovascular Biomarkers and GLP-1 Safety Assessment Before starting GLP-1 therapy, your provider may review cardiovascular biomarkersincluding blood pressure, heart rate, lipid profiles, and renal functionto establish a baseline safety profile