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Beyond its high prevalence and disease burden, DKD markedly increases cardiovascular disease (CVD) risk and mortality [4]
doi: 10.3390/ijms221910822
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Exendin-4treated Ldlr / mice on an HCD not only showed smaller atherosclerotic lesions but also a more than 50% reduction in blood leukocytes, including Ly-6C hi monocytes and neutrophils (7), suggesting downregulation of bone marrow hematopoiesis in response to activation of the GLP-1R
