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Third, the in vitro experiments were conducted using only one cell line rather than multiple, which may not fully represent the biological variability across different cell types

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10.1358/mf.1998.20.8.487502 17 CummingsD

Nature Reviews Endocrinology 6689697

In the present study, significant reductions in testosterone, LH, LH/FSH ratio, fasting insulin, and HOMA-IR were observed in the semaglutide-intensified treatment group compared to baseline measurements after 12 weeks of semaglutide treatment
