retatrutide phase 2 weight loss results 🚨Breaking: Retatrutide's first 3 T2D data just dropped. ▸ A1C: −2.0% at 40 weeks ▸ Weight: −36.6 lbs (−16.8%) at 12 mg ▸ No plateau — curve still descending Retatrutide: What It Is &

A recent meta-analysis of 14 studies [2] has shown that GLP-1RAs, such as liraglutide, semaglutide, and exenatide, cross the blood-brain barrier (BBB) and affect the brain at all levels, from the molecular to the level of neuronal networks

This convenient once-daily pill is an oral GLP-1 receptor agonist that aims to regulate blood sugar levels and achieve body weight reduction, potentially offering a safe and effective treatment option for diabetes care

Correction of diet-induced hyperglycemia, hyperinsulinemia, and skeletal muscle insulin resistance by moderate hyperleptinemia

5.2 Rare serious adverse events: individualized screening and monitoring Gallbladder disease: GLP-1RAs are associated with an increased risk of gallbladder-related events, often occurring in parallel with mechanisms such as rapid weight loss and cholestasis (143)

One other way you can think about it is a PBM is like a health insurance company, but they just do it for the pharmaceutical benefit and not all the other stuff that the health insurance companies do